March 12, 2019


Links to read

A summary

David Sinclair’s excerpt from radio interview

David takes

  • 1 gr of Nicotinamide Mononucleotide (NMN)
  • 0.5 gr of resveratrol

every morning mixed in with some yogurt.

Note – he doesn’t get specific with brands, but he does say the resveratrol is in powder form, left over from clinical trials a while back. Sirtuins are genes found to control aging in yeast cells. There are 7 of them in humans (5 in yeast). They protect all organisms from deterioration and disease

“[Sirtuins] sense when we’re hungry/exercising, and send out the troops to defend us”
“When you put more sirtuins into a yeast cell or a mouse, it lives 5-20% longer”

NMN and Resveratrol are molecules which essentially mimic the effects of the sirtuin genes

“You can think of resveratrol as the accelerator pedal for the sirtuin genes, and NMN as the fuel”
“Resveratrol steps on the accelerator pedal of the sirtuin enzymes”

So you need the fuel (NMN) for resveratrol to work.

Effect of Nicotinamide Mononucleotide (NMN) on humans

What is intermittent fasting

A (very much) simplified guide,

and also some more information about the topic of autophagy